L-Methionine

CAS No.: 63-68-3
Molecular formular: C₅H₁₁NO₂S
Molecular weight: 149.21

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Shijiazhuang Jirong Pharmaceutical Co., Ltd.

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L-Methionine	AJI97	USP2025	EP11	JP18
Appearance	White crystals or crystalline powder	White crystals	White or almost white, crystalline powder or colourless crystals	White crystals or crystalline powder
ldentification	Conform	Conform	IR:Conform to CRS Spectrum	IR: Conform to CRS Spectrum
State of solution (Transmittance)	Clear and colorless, ≥98.0%	/	/	/
Specific rotation	+23.0° ~ +24.0°	/	+22.5° ~ +24.0° (dried substance)	+21.0° ~ +25.0°
Optical rotation	/	+22.4º ~ +24.7º	/	/
Chloride	≤0.020%	≤0.05%	≤200ppm	≤0.021%
Sulfate	≤0.020%	≤0.03%	≤300ppm	≤0.028%
Ammonium	≤0.02%	/	≤200ppm	≤0.02%
Iron	≤10ppm	≤30ppm	≤10ppm	/
Heavy metals	≤10ppm	/	/	≤20ppm
Arsenic	≤1ppm	/	/	≤2ppm
Other amino acids	Conform	/	/	/
Loss on drying	≤0.20%	≤0.3%	≤0.5%	≤0.30%
Residue on ignition	≤0.10%	≤0.4%	≤0.1%	≤0.1%
pH	5.6~ 6.1	5.6 ~ 6.1	5.5 ~ 6.5	5.2 ~ 6.2
Assay	99.0% ~ 101.0%	98.5% ~ 101.5% (on the dried basis)	99.0% ~ 101.0% (dried substance)	≥98.5%
Related compounds	/	Methionine sulfoxide: ≤0.1%	Unspecified impurities: each impurity: ≤ 0.10%	Conform
		N-Acetyl-D,L-methionine: ≤0.2%	Unspecified impurities: each impurity: ≤ 0.10%
		Any unspecified impurity: ≤0.1%	Total: ≤ 0.3%
		Total unspecified impurities: ≤0.30%	Total: ≤ 0.3%
Appearance of solution	/	/	Solution S is clear and colourless	Clear and colorless